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What is High-Throughput Screening of CD4 T Cells about?

This study presents a high-throughput, HLA-independent method for detecting and characterizing tumor antigen-specific CD4 T cells in healthy donors and melanoma patients. The results indicate that while healthy individuals have comparable frequencies of naive tumor-specific CD4 T cells to those specific for infectious agents, melanoma patients show low frequencies that can increase following immunotherapy. This approach facilitates the monitoring of CD4 T cell responses and may accelerate the development of

Author

Wang Jianwei

Language

EN