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Can I read Immunometabolism and Immune Response Regulate Macrophage Function in Atherosclerosis on EtoBox?
Immunometabolism and Immune Response Regulate Macrophage Function in Atherosclerosis by Sheng Xue; Zhe Su; Dacheng Liu is a Medicine article available to read on EtoBox.
What is Immunometabolism and Immune Response Regulate Macrophage Function in Atherosclerosis about?
Macrophages are crucial in the progression of atherosclerotic cardiovascular disease (ASCVD). In the atherosclerotic lesions, macrophages play a central role in maintaining inflammatory response, promoting plaque development, and facilitating thrombosis. Increasing studies indicate that metabolic reprogramming and immune response mediate macrophage functional changes in all stages of atherosclerosis. In this review article, we explain how metabolic changes in glycolysis, oxidative phosphorylation, the tricarboxylic acid cycle, fatty acid synthesis, fatty acid oxidation, and cholesterol metabolism regulate macrophage function in atherosclerosis. We discuss how immune response to oxidized lipids regulate macrophage function in atherosclerosis. Additionally, we explore how abnormal metabolism leads to macrophage mitochondrial dysfunction in atherosclerosis.
Who reads Immunometabolism and Immune Response Regulate Macrophage Function in Atherosclerosis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sheng Xue; Zhe Su; Dacheng Liu
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)