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Can I read Disorders of Bone Remodeling on EtoBox?
Disorders of Bone Remodeling by Xu Feng; Jay M. McDonald is a Medicine article available to read on EtoBox.
What is Disorders of Bone Remodeling about?
The skeleton provides mechanical support for stature and locomotion, protects vital organs, and controls mineral homeostasis. A healthy skeleton must be maintained by constant bone modeling to carry out these crucial functions throughout life. Bone remodeling involves the removal of old or damaged bone by osteoclasts (bone resorption) and the subsequent replacement of new bone formed by osteoblasts (bone formation). Normal bone remodeling requires a tight coupling of bone resorption to bone formation to guarantee no alteration in bone mass or quality after each remodeling cycle. However, this important physiological process can be derailed by a variety of factors, including menopause-associated hormonal changes, age-related factors, changes in physical activity, drugs, and secondary diseases, which lead to the development of various bone disorders in both women and men. We review the major diseases of bone remodeling, emphasizing our current understanding of the underlying pathophysiological mechanisms.
Who reads Disorders of Bone Remodeling?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Xu Feng; Jay M. McDonald
- Publisher
- Annual Reviews
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)