Opening book details…
Can I read Development and Validation of Nomograms Predicting the Overall and the Cancer-Specific Survival in Endometrial Cancer Patients on EtoBox?
Development and Validation of Nomograms Predicting the Overall and the Cancer-Specific Survival in Endometrial Cancer Patients by Li, Xingchen; Fan, Yuan; Dong, Yangyang; Cheng, Yuan; Zhou, Jingyi; Wang, Zhiqi; Li, Xiaoping; Wang, Jianliu is a Medicine article available to read on EtoBox.
What is Development and Validation of Nomograms Predicting the Overall and the Cancer-Specific Survival in Endometrial Cancer Patients about?
Background: The present study was aimed at developing nomograms estimating the overall survival (OS) and cancer-specific survival (CSS) of endometrial cancer (EC)-affected patients. Patients and Methods: We retrospectively collected 145,445 EC patients between 2004 and 2015 from the Surveillance, Epidemiology, and End Results (SEER) database. Independent prognostic factors were identified via univariate and multivariate Cox analyses. These risk factors were used to establish nomograms to predict 3- and 5-year OS and CSS rates. Internal and external data were used for validation. The predictive accuracy and discriminative ability were measured by using concordance index (C-index) and risk group stratification. Results: A total of 63,510 patients were collected and randomly assigned into the training cohort (n = 42,340) and the validation cohort (n = 21,170). Age at diagnosis, marital status, tumor size, histologic type, lymph node metastasis, tumor grade, and clinical stage were identified as independent prognostic factors for OS and CSS (p < 0.05 according to multivariate Cox analysis) and were further used to construct the nomograms. The area under the receiver operating character
Who reads Development and Validation of Nomograms Predicting the Overall and the Cancer-Specific Survival in Endometrial Cancer Patients?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Li, Xingchen; Fan, Yuan; Dong, Yangyang; Cheng, Yuan; Zhou, Jingyi; Wang, Zhiqi; Li, Xiaoping; Wang, Jianliu
- Publisher
- Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2014- (ISSN 2296-858X)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)