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Amica: an Interactive and User-friendly Web-platform for the Analysis of Proteomics Data by Sebastian Didusch; Moritz Madern; Markus Hartl; Manuela Baccarini is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Amica: an Interactive and User-friendly Web-platform for the Analysis of Proteomics Data about?

## Abstract ## Background Quantitative proteomics has become an increasingly prominent tool in the study of life sciences. A substantial hurdle for many biologists are, however, the intricacies involved in the associated high throughput data analysis. ## Results In order to facilitate this task for users with limited background knowledge, we have developed amica, a freely available open-source web-based software that accepts proteomic input files from different sources. amica provides quality control, differential expression, biological network and over-representation analysis on the basis of minimal user input. Scientists can use amica’s query interface interactively to compare multiple conditions and rapidly identify enriched or depleted proteins. They can visualize their results using customized output graphics, and ultimately export the results in a tab-separated format that can be shared with collaborators. The code for the application, input data and documentation can be accessed online at https://github.com/tbaccata/amica and is also incorporated in the web application. ## Conclusions The strong emphasis on dynamic user interactions, the integration of various databases and

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Author

Sebastian Didusch; Moritz Madern; Markus Hartl; Manuela Baccarini

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)