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What is Cefiderocol Resistance in KPC K. pneumoniae about?

The study investigates a novel mechanism of cefiderocol (FDC) resistance in KPC-producing Klebsiella pneumoniae, highlighting the role of plasmid-located ferric citrate transport systems. Analysis of clinical isolates revealed that the presence of specific plasmids, particularly pKPN, contributes to increased FDC minimum inhibitory concentrations (MICs) in various K. pneumoniae clones. This research underscores the importance of understanding plasmid interactions in the context of antibiotic resistance in p

Author

kenan asık

Language

EN