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Can I read Diastereoselective reduction and carboncarbon bond formation of α-keto esters/amides with SmI2 on EtoBox?
Diastereoselective reduction and carboncarbon bond formation of α-keto esters/amides with SmI2 by Shin-ichi Fukuzawa; Manabu Miura; Hiroshi Matsuzawa is a Chemistry article available to read on EtoBox.
What is Diastereoselective reduction and carboncarbon bond formation of α-keto esters/amides with SmI2 about?
The stereoselective reduction of a-keto esters/a-keto amides, which have various chiral auxiliaries using SmI 2 , is examined. 2(S)-Methoxymethylpyrrolidine, 1,1,2(S)-and 1,1,2(R)-triphenylethanediol were found to be suitable chiral auxiliaries that produced the corresponding a-hydroxy ester and amide in good diastereoselectivity with satisfactory yields. Allylation, the Reformatsky-type reaction, and the ketyl-alkene coupling reaction with the 1,1,2(R)-triphenylethanediol and 2(S)-methoxymethylpyrrolidine, derivative of the a-keto ester/amide proceeded smoothly with high diastereoselectivity.
Who reads Diastereoselective reduction and carboncarbon bond formation of α-keto esters/amides with SmI2?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Shin-ichi Fukuzawa; Manabu Miura; Hiroshi Matsuzawa
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0040-4039)
- Published
- 2001
- Language
- EN
- Field
- Chemistry (Physical Sciences)