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Can I read Proteomic composition of Nipah virus-like particles on EtoBox?
Proteomic composition of Nipah virus-like particles by Natalia Mara Vera-Velasco; Maria Jesús García-Murria; Manuel M. Sánchez del Pino; Ismael Mingarro; Luis Martinez-Gil is a Chemistry article available to read on EtoBox.
What is Proteomic composition of Nipah virus-like particles about?
## Biological significance: Traditionally viral particles have been described as pure entities carrying only viral-derived proteins. advances in proteomics are changing this simplified view. host proteins have been identified in many viruses (especially in enveloped viruses). these cell-derived proteins participate in multiple steps in the viral life cycle and might be as important for the survival of the virus as any other viral-encoded protein. in this work, we analyze utilizing lc-ms/ms the cellular proteins incorporated or bound to the virions of nipah virus (niv), an emerging, highly pathogenic, zoonotic virus from the paramyxoviridiae family. furthermore, we analyzed the ratio between cellular and viral proteins and among the viral f, g and m proteins in the viral particles. the characterization of the nipah virus-human interactions occurring in the virion might facilitate the development of new therapeutic and prophylactic therapies for this viral illness.
Who reads Proteomic composition of Nipah virus-like particles?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Natalia Mara Vera-Velasco; Maria Jesús García-Murria; Manuel M. Sánchez del Pino; Ismael Mingarro; Luis Martinez-Gil
- Publisher
- Elsevier BV
- Published
- 2017
- Language
- EN
- Field
- Chemistry (Physical Sciences)