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A25 The Rising Global Incidence Of Pediatric Inflammatory Bowel Disease: A Systematic Review Of Population-based Studies by E Kuenzig; S G Fung; L Marderfeld; J W Mak; G G Kaplan; S C Ng; D C Wilson; F L Cameron; P Henderson; P G Kotze; E I Benchimol; InsightScope is a Medicine article available to read on EtoBox.

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## Abstract ## Background The incidence of inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), is increasing internationally, particularly in developing nations where rates were historically low. Previous reports of the incidence and prevalence of pediatric-onset IBD have identified a paucity of population-based studies. ## Aims We reviewed the global trends in incidence of pediatric IBD using evidence from population-based studies. ## Methods (PROSPERO CRD42019125193) We systematically reviewed studies indexed in MEDLINE, EMBASE, Airiti Library, and SciELO from 01/2010-02/2020 to identify population-based studies reporting the incidence of pediatric-onset IBD, CD, and UC. Included studies combined childhood and adolescent-onset IBD (onset <21y). Changes in incidence since 2000 were plotted by continent, with data from 2000–09 provided by our previous systematic review1. To depict trends, multiple times points reported in single studies were connected on graphs. When incidence was reported as an aggregated estimate over a range of years, data was plotted using the midpoint of the interval. ## Results Of 8096 abstracts screened, 74 studies d

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Author

E Kuenzig; S G Fung; L Marderfeld; J W Mak; G G Kaplan; S C Ng; D C Wilson; F L Cameron; P Henderson; P G Kotze; E I Benchimol; InsightScope

Publisher

Oxford University Press (OUP)

Published

2021

Language

EN

Field

Medicine (Health Sciences)