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This study presents nicotinamide-loaded peptoid nanotubes (NAM-PNTs) as a novel delivery system for enhancing ATP regeneration in acutely injured brains, addressing challenges in cell-specific delivery of NAD+ precursors. NAM-PNTs demonstrated significant therapeutic benefits, including improved cell viability and reduced inflammation in models of oxygen-glucose deprivation and hypoxia-ischemia. The findings suggest that NAM-PNTs have potential for targeted energy restoration in neonatal brain injuries, mar

Author

Pushpendra Singh

Language

EN