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Management of Sinistral Portal Hypertension after Pancreaticoduodenectomy by Nabeel Mansour; Simon Sirtl; Martin K. Angele; Moritz Wildgruber is a Medicine article available to read on EtoBox.

What is Management of Sinistral Portal Hypertension after Pancreaticoduodenectomy about?

## Abstract ## Background Sinistral, or left-sided, portal hypertension (SPH) is a rare cause of upper gastrointestinal (GI) hemorrhage resulting from obstruction of the splenic vein. Venous drainage from the spleen via collaterals can result in venous hemorrhage into both the retroperitoneal and intra-abdominal spaces due to increased venous blood pressure in peripancreatic and gastroduodenal vasculature. SPH can occur secondary to pancreatitis with thrombosis of the splenic vein. Another possible cause is the surgical ligation of the splenic vein as part of pancreaticoduodenectomy (PD). Although splenectomy has been traditionally considered as the treatment of choice to relieve venous hypertension, individual concepts for each patient have to be developed. Considering the venous collateral drainage pathways, a comprehensive approach involving surgical, endoscopic, and interventional radiology interventions may be necessary to address the underlying cause of variceal bleeding. Among these approaches, splenic artery embolization (SAE) has demonstrated efficacy in mitigating the adverse effects associated with elevated venous outflow pressure. ## Summary This review summarizes key i

Who reads Management of Sinistral Portal Hypertension after Pancreaticoduodenectomy?

Author

Nabeel Mansour; Simon Sirtl; Martin K. Angele; Moritz Wildgruber

Publisher

S. Karger AG

Published

2024

Language

EN

Field

Medicine (Health Sciences)