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What is MST2 Kinase Role in Tumor Suppression about?

1) The proapoptotic kinase MST2 acts in a novel tumor suppression pathway that limits the positive effects of Raf-MAPK signaling in cancer cells. 2) Raf-1 kinase sequesters and inhibits MST2, preventing its dimerization and activation. This interaction suppresses MST2 phosphorylation and kinase activity independent of Raf-1

Author

franciscrick69

Language

EN