Opening book details…
Can I read The Impact of Enriched Resistant Starch Type‐2 Cookies on the Gut Microbiome in Hemodialysis Patients: A Randomized Controlled Trial on EtoBox?
The Impact of Enriched Resistant Starch Type‐2 Cookies on the Gut Microbiome in Hemodialysis Patients: A Randomized Controlled Trial by Julie Ann Kemp; Bruna Regis de Paiva; Henrique Fragoso dos Santos; Hugo Emiliano de Jesus; Hannah Craven; Umer Z. Ijaz; Natalia Alvarenga Borges; Paul G. Shiels; Denise Mafra is a Medicine article available to read on EtoBox.
What is The Impact of Enriched Resistant Starch Type‐2 Cookies on the Gut Microbiome in Hemodialysis Patients: A Randomized Controlled Trial about?
## Introduction Resistant starch type‐2 (RS2) can mitigate inflammation and oxidative stress in hemodialysis (HD) patients. However, there is still a lack of knowledge on the impact of the RS2 on the gut microbiota community in these patients. Thus, this study aims to evaluate the effects of enriched RS2 cookies on the gut microbiome in HD patients. ## Methods and Results This comprises a randomized, double‐blind, placebo‐controlled trial of age‐, sex‐, and BMI‐matched patients and controls. The RS2 group receives enriched RS2 cookies (16 g d^‐1^ of Hi‐Maize 260, Ingredion) for 4 weeks, while the placebo group received cookies made with manioc flour. Fecal microbiota composition is evaluated by the 16S ribosomal RNA gene. Analysis of the microbiota reveals that Pielou's evenness is significantly decreased after RS2 supplementation. Notably, it is observed that RS2 intervention upregulates significantly 8 Amplicon Sequencing Variants (ASV's), including Roseburia and Ruminococcus gauvreauii, which are short‐chain fatty acids (SCFA) producers. Furthermore, it is associated with the downregulation of 11 ASVs, such as the pro‐inflammatory Dialister. ## Conclusions RS2 intervention for 4
Who reads The Impact of Enriched Resistant Starch Type‐2 Cookies on the Gut Microbiome in Hemodialysis Patients: A Randomized Controlled Trial?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Julie Ann Kemp; Bruna Regis de Paiva; Henrique Fragoso dos Santos; Hugo Emiliano de Jesus; Hannah Craven; Umer Z. Ijaz; Natalia Alvarenga Borges; Paul G. Shiels; Denise Mafra
- Publisher
- Wiley
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)