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Can I read Nucleotides. Part XXXVI. Syntheses and biological characterization of phosphorothioate analogues of (3′–5′)adenylate trimer on EtoBox?
Nucleotides. Part XXXVI. Syntheses and biological characterization of phosphorothioate analogues of (3′–5′)adenylate trimer by Ramamurthy Chambala; Robert W. Sobol; Ning Kon; Robert J. Suhadolnik; Wolfgang Pfleiderer is a Chemistry article available to read on EtoBox.
What is Nucleotides. Part XXXVI. Syntheses and biological characterization of phosphorothioate analogues of (3′–5′)adenylate trimer about?
## Abstract The four protected diastereoisomcrs 7a/7b and 8a/8b __P__‐thioadenylyl‐(3′–5′)‐__P__‐thioadenylyI‐(3′–5′)‐adenosine were synthesized, separated, and deblocked to the free oligonucleotides (__Scheme__). Biochemical characterization of these (3′–5′)phosphorothioate analogues of adenyiate trimer indicate that these compounds, and the corresponding 5′‐monophosphates, neither bind to nor activate RNase L, and are considered to be valuable control compounds in screening experiments.
Who reads Nucleotides. Part XXXVI. Syntheses and biological characterization of phosphorothioate analogues of (3′–5′)adenylate trimer?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Ramamurthy Chambala; Robert W. Sobol; Ning Kon; Robert J. Suhadolnik; Wolfgang Pfleiderer
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 0018-019X)
- Published
- 1991
- Language
- EN
- Field
- Chemistry (Physical Sciences)