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A Clinical-radiomics Nomogram May Provide a Personalized 90-Day Functional Outcome Assessment for Spontaneous Intracerebral Hemorrhage by Zuhua Song; Zhuoyue Tang; Huan Liu; Dajing Guo; Jinhua Cai; Zhiming Zhou is a Medicine article available to read on EtoBox.

What is A Clinical-radiomics Nomogram May Provide a Personalized 90-Day Functional Outcome Assessment for Spontaneous Intracerebral Hemorrhage about?

## Objectives: To develop and validate a noncontrast computed tomography (ncct)-based clinical-radiomics nomogram to identify spontaneous intracerebral hemorrhage (sich) patients with a poor 90-day prognosis on admission. ## Methods: In this double-center retrospective study, data from 435 patients with sich (training cohort: n = 244; internal validation cohort: n = 104; external validation cohort: n = 87) were reviewed. the radiomics score (rad-score) was calculated based on the coefficients of the selected radiomics features. a clinical-radiomics nomogram was developed by using independent predictors of poor outcome at 90 days through multivariate logistic regression analysis in the training cohort and was validated in the internal and external cohorts. ## Results: At 90 days, 200 of 435 (46.0%) patients had a poor prognosis. the clinical-radiomics nomogram was developed by six independent predictors namely midline shift, ncct time from sich onset, glasgow coma scale score, serum glucose, uric acid, and rad-score. in identifying patients with poor prognosis, the clinical-radiomics nomogram showed an area under the receiver operating characteristic curve (auc) of 0.81 in the train

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Author

Zuhua Song; Zhuoyue Tang; Huan Liu; Dajing Guo; Jinhua Cai; Zhiming Zhou

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)