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Can I read Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416 on EtoBox?
Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416 by Bulbul Pandit; Yanjun Sun; Ping Chen; Dan L. Sackett; Zhigen Hu; Wendy Rich; Chenglong Li; Andrew Lewis; Kevin Schaefer; Pui-Kai Li is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416 about?
A series of combretastatin A-4 analogs derived from the ATP competitive, VEGF receptor tyrosine kinase inhibitor, SU5416 were synthesized. The cytotoxic effects of the analogs were evaluated against PC-3 and MDA-MB-231 cancer cell lines, as well as their abilities to inhibit tubulin polymerization. Results are compared to those of compound 1, our lead compound previously reported.
Who reads Structure–activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Bulbul Pandit; Yanjun Sun; Ping Chen; Dan L. Sackett; Zhigen Hu; Wendy Rich; Chenglong Li; Andrew Lewis; Kevin Schaefer; Pui-Kai Li
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0968-0896)
- Published
- 2006
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)