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Circularly polarised MF (500 μT 50 Hz) does not acutely suppress melatonin secretion from cultured Wistar rat pineal glands by H.M. Tripp; G.R. Warman; J. Arendt is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Magnetic fields (MF, 50 Hz) have been proposed to affect melatonin production in mammals; however, there is very little data about the mechanism by which this possible interaction may occur. Here we describe results from the first study in which circularly polarised 50 Hz MF have been administered to isolated pineals in highly controlled conditions. Melatonin release from isolated Wistar rat pineal glands, dissected 2 h after light onset ZT 2, was measured in a flow through culture system, during and after exposure to a 4 h MF similar in nature and magnitude to that produced in extremely close proximity to a high voltage power line (500 μT 50 Hz circularly polarised). Melatonin release from isolated pineals was comparable to that observed in previous studies, plateauing to ∼100 pg/ml/30 min. No significant alterations in pineal melatonin release were caused by exposure to the MF when compared to sham exposure (< 1 μT). These results suggest that if the circadian system is acutely responsive to MF exposure of this nature, an intact circadian axis may be necessary in order to observe an effect on the production on melatonin from the pineal gland. Bioelectromagnetics 24:11

Who reads Circularly polarised MF (500 μT 50 Hz) does not acutely suppress melatonin secretion from cultured Wistar rat pineal glands?

Author

H.M. Tripp; G.R. Warman; J. Arendt

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0197-8462)

Published

2003

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)