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Can I read Bortezomib treatment of steroid‐refractory Evans syndrome in children on EtoBox?
Bortezomib treatment of steroid‐refractory Evans syndrome in children by Serina B. Beydoun; Yogindra Persaud; Jennifer Lafferty; Michael U. Callaghan; Süreyya Savaşan is a Medicine article available to read on EtoBox.
What is Bortezomib treatment of steroid‐refractory Evans syndrome in children about?
## Abstract Treatment of refractory Evans syndrome (ES) remains a challenge in hematology practice. Due to rarity of this condition, evidence‐based approaches are limited and often treatment choices stem from small case series or anecdotal experiences. There is mounting evidence that some patients have genetic defects that could be targeted with promising preliminary results. Here, we describe three very refractory pediatric ES cases treated on bortezomib without adverse effects. Two of the three patients had dramatic and long‐lasting recovery that started following the initial doses of the drug. Clinical trials to assess the role of bortezomib in ES treatment are warranted.
Who reads Bortezomib treatment of steroid‐refractory Evans syndrome in children?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Serina B. Beydoun; Yogindra Persaud; Jennifer Lafferty; Michael U. Callaghan; Süreyya Savaşan
- Publisher
- Wiley
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)