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Lymphoproliferative Responses to Autologous Tumor Extracts as Prognostic Indicators in Patients with Resected Breast Cancer by G. B. Cannon; J. H. Dean; B. Herberman; M. Keels; C. Alford is a Medicine article available to read on EtoBox.

What is Lymphoproliferative Responses to Autologous Tumor Extracts as Prognostic Indicators in Patients with Resected Breast Cancer about?

## Abstract Patients with operable breast cancer were tested postoperatively to assess lymphoproliferative responses. Patients with lymphocytes capable of recognizing and proliferating in response to autologous tumor extracts had a significantly longer disease‐free interval than those with a low response to their autologous extract. In this group of patients, immunological responses to autologous tumors predicted subsequent clinical course better than pathological evaluation based on tumor presence in axillary lymph nodes. Low or negative reactivity to autologous tumor often was not accompanied by a general, impaired ability to respond in LP assays. In fact, patients with low autologous tumor response and normal MLC were at a particularly high risk for recurrence.

Who reads Lymphoproliferative Responses to Autologous Tumor Extracts as Prognostic Indicators in Patients with Resected Breast Cancer?

Author

G. B. Cannon; J. H. Dean; B. Herberman; M. Keels; C. Alford

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

1981

Language

EN

Field

Medicine (Health Sciences)