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Natural history of gastric adenomas in patients with familial adenomatosis Coli/Gardner's syndrome by Mitsuo Iida; Tsuneyoshi Yao; Hideaki Itoh; Hidenobu Watanabe; Toshiyuki Matsui; Akinori Iwashita; Masatoshi Fujishima is a Medicine article available to read on EtoBox.

The natural history of gastric adenomas was studied in 26 patients with familial adenomatosis coli (FAC)/Gardner's syndrome. The patients were followed for an average of 6.8 years (1 year, 5 months to 15 years 4 months) and examined repeatedly using gastric radiography, endoscopy, and biopsy. Gastric adenomas were present in 13 (50%). During the follow-up period, there was a new appearance of gastric adenomas in six patients but no distinct change in number, size, and histologic features in the remainiing seven patients. In a 51-year-old man, an antral adenoma that measured 13 mm in diameter and had an irregular central depression did not change in size or morphology during 4 years and 1 month, but malignant change was evident at the time of endoscopic biopsy. The findings indicate that in patients with this disease, gastric adenomas require careful repeated follow-up examinations using endoscopic biopsy and, if feasible, endoscopic removal is recommended. Camer61:605-611,1988. ## HE OCCURRENCE of gastric lesions previously has T been considered rare in familial adenomatosis coli (FAC) or Gardner's syndrome.'.' Since 1974, however, gastric lesions have been observed in approximatel

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Author
Mitsuo Iida; Tsuneyoshi Yao; Hideaki Itoh; Hidenobu Watanabe; Toshiyuki Matsui; Akinori Iwashita; Masatoshi Fujishima
Publisher
YouScribe
Published
1988
Language
EN
ISBN
9782820610331
Field
Medicine (Health Sciences)