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Fasting and Postprandial Levels of Ghrelin, Leptin and Insulin in Lean, Obese and Anorexic Subjects by Emilia Korek; Hanna Krauss; Magdalena Gibas-Dorna; Justyna Kupsz; Małgorzata Piątek; Jacek Piątek is a Medicine article available to read on EtoBox.
What is Fasting and Postprandial Levels of Ghrelin, Leptin and Insulin in Lean, Obese and Anorexic Subjects about?
## Introduction Ghrelin, leptin and insulin are involved in neurohormonal regulation of energetic homeostasis. ## Aim We investigated the correlation between nutritional status and plasma levels of leptin, ghrelin and insulin in lean, obese and anorexic subjects. ## Material and methods Nineteen obese and 18 anorexic adults were enrolled in the study. Seventeen adults with normal body mass index (BMI) served as controls. Blood samples were taken twice: before breakfast and 2 h after breakfast. Fasting and postprandial ghrelin, leptin and insulin were examined. The following correlations were estimated: between BMI and basal level of tested hormones, between insulin and ghrelin, and between insulin and leptin. The threshold level of significance was __p__ ≤ 0.05 for all calculations. ## Results Basal insulin level was lowest in anorexic patients and greatest in obese subjects. Fasting plasma ghrelin was lower in obesity and higher in anorexia as compared with the controls. Comparing with controls, fasting leptin levels were higher in obese and lower in anorexic subjects. There was positive correlation between BMI and basal leptin level in obesity. A significant postprandial increase
Who reads Fasting and Postprandial Levels of Ghrelin, Leptin and Insulin in Lean, Obese and Anorexic Subjects?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Emilia Korek; Hanna Krauss; Magdalena Gibas-Dorna; Justyna Kupsz; Małgorzata Piątek; Jacek Piątek
- Publisher
- Termedia Sp. z.o.o.; Termedia Publishing House Ltd. (ISSN 1895-5770)
- Published
- 2013
- Language
- EN
- Field
- Medicine (Health Sciences)