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Antioxidant and Hepatic Protective Effects of Lotus Root Hot Water Extract with Taurine Supplementation in Rats Fed a High Fat Diet by Huan Du; Xu Zhao; Jeong-Soon You; Ji-Yeon Park; Sung-Hoon Kim; Kyung-Ja Chang is a Medicine article available to read on EtoBox.

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## Background: Nelumbo nucifera, known as sacred lotus, is a well-known medicinal plant and this lotus root is commonly used as food compared to different parts of this plant. this study was conducted to investigate the antioxidant and hepatic protective effects of lotus root hot water extract with taurine supplementation in high fat diet-induced obese rats. ## Methods: Thirty-two male sprague-dawley rats (4-week-old) were randomly divided into four groups (n=8) for 6 weeks (normal diet, n group; high fat diet, hf group; high fat diet + lotus root hot water extract, hfr group; high fat diet + lotus root hot water extract + taurine, hfrt group). lotus root hot water extract was orally administrated (400 mg/kg/day) to hfr and hfrt groups and the same amount of distilled water was orally administered to n and hf groups. taurine was supplemented by dissolving in feed water (3% w/v). ## Results: The activities of glutamate oxaloacetate transaminase and glutamate pyruvate transaminase in serum were lower in hfr and hfrt groups compared to hf group. thiobarbituric acid reactive substance contents in all groups fed a high fat diet were higher compared to n group. the activities of hepatic

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Author

Huan Du; Xu Zhao; Jeong-Soon You; Ji-Yeon Park; Sung-Hoon Kim; Kyung-Ja Chang

Publisher

BioMed Central; Springer (Biomed Central Ltd.); BioMed Central Ltd.; [Basel Switzerland]: Karger; London: 2009-; Springer Science and Business Media LLC; S. Karger AG; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1021-7770)

Published

2010

Language

EN

Field

Medicine (Life Sciences)