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Appropriateness of antibiotics for medical prophylaxis: evaluation of data from the Italian PPS-2 by A Cremona; J Garlasco; I Gintoli; A D'Ambrosio; F Quattrocolo; C Vicentini; C M Zotti is a Health Professions article available to read on EtoBox.

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## Abstract ## Background Antibiotics (AB) are administered for medical prophylaxis (MP) to prevent infectious complications. The second national point prevalence survey (PPS) of healthcare-associated infections and AB use was conducted in Italy in 2016-2017. The survey found MP accounted for nearly 25% of all registered ABs, more than twice the EU/EEA proportion. The aim of this study was to evaluate how many ABs were administered for MP and how frequently general indications were followed. ## Methods Data from the PPS were used to evaluate the prevalence of indications for MP over the total number of ABs, the proportion - among these indications - of those justified by a motivation in the patients' charts, and the prevalence of ABs considered appropriate for MP. The evaluation was made in 12 hospitals out of 14 participating in the PPS in Piedmont, chosen on the basis of patient traceability. According to national guidelines, the indications for MP that were considered appropriate in this study were: Trimethoprim/sulfamethoxazole for P. carinii pneumonia, Rifaximin for diverticulitis, Penicillin for Streptococcal infections and for splenectomized patients, and Rifampin for TB inf

Who reads Appropriateness of antibiotics for medical prophylaxis: evaluation of data from the Italian PPS-2?

Author

A Cremona; J Garlasco; I Gintoli; A D'Ambrosio; F Quattrocolo; C Vicentini; C M Zotti

Publisher

Oxford University Press (OUP)

Published

2020

Language

EN

Field

Health Professions (Health Sciences)