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What is Quinolone Antibiotics: Development & Resistance about?

Quinolone antibiotics, first developed in the 1960s, have evolved from narrow-spectrum agents to broad-spectrum antibiotics effective against various bacterial infections. They work by inhibiting bacterial nucleic acid synthesis, but resistance has emerged due to overuse, leading to modifications in their structure to enhance efficacy. The review discusses the development, mechanisms of action, resistance, and future strategies for improving quinolone antibiotics.

Author

Mouse et forshita

Language

EN