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The Significance of Radiotherapy Treatment Duration in Intracranial Ependymoma by Arnold C Paulino; B-Chen Wen is a Medicine article available to read on EtoBox.

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Purpose: To determine if radiation therapy treatment duration has an impact on the outcome of intracranial ependymoma. Methods and Materials: From 1965 to 1997, 34 patients with intracranial ependymoma were seen and treated with postoperative radiotherapy (RT). There were 26 male and 8 female patients with a median age of 14 years (range, 18 months to 60 years). Tumor location was infratentorial in 23 (67.6%) and supratentorial in 11 (32.4%). Pathology was low-grade in 25 (73.5%) and high-grade in 9 (26.5%). Two (5.9%) patients had M؉ disease at initial diagnosis. Gross total resection was achieved in 12 (35.3%), subtotal resection in 19 (55.9%), and biopsy alone in 3 (8.8%). Median RT dose to the primary site was 5400 cGy (range, 4500 cGy to 6600 cGy). The entire neuraxis was treated in 14 (41.2%), whole brain in 9 (26.5%), and the primary site alone in 11 (32.4%). Median radiotherapy treatment duration was 43 days (range, 26 to 122 days). Patients treated with craniospinal RT were more likely to have treatment duration of >50 days. Median follow-up was 108 months (range, 24 to 252 months). Results: The 5-, 10-, and 15-year overall survival rates were 71.5%, 63.3%, and 55.4%. Loca

Who reads The Significance of Radiotherapy Treatment Duration in Intracranial Ependymoma?

Author

Arnold C Paulino; B-Chen Wen

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2000

Language

EN

Field

Medicine (Health Sciences)