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Multicystic and Diffuse Malignant Peritoneal Mesothelioma in Children by Sophie Vermersch; Alexis Arnaud; Daniel Orbach; Nicolas Andre; Claire Berger; Vahan Kepenekian; Cécile Brigand; Brice Fresneau; Marie‐Laurence Poli‐Merol; Cyril Habougit; François Varlet; Aurélien Scalabre is a Medicine article available to read on EtoBox.
What is Multicystic and Diffuse Malignant Peritoneal Mesothelioma in Children about?
## Abstract ## Background Malignant and multicystic peritoneal mesotheliomas are extremely rare tumors in children, developing from mesothelial cells. No specific guidelines are available at this age. ## Methods We performed a retrospective analysis of all identified children (< 18‐year‐old) treated in France from 1987 to 2017 for a diffuse malignant peritoneal mesothelioma (DMPM) or a multicystic peritoneal mesothelioma (MCPM). ## Results Fourteen patients (5 males and nine females), aged 2.2 to 17.5 years, were included. The most frequent presenting symptoms were abdominal pain, ascitis, and alteration in the general condition. Eight patients had epithelioid mesothelioma, three had biphasic mesothelioma, and three had MCPM. Eight patients with DMPM diagnosis received cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). Among them, six patients had neoadjuvant systemic chemotherapy, one patient, post‐operative chemotherapy, and one patient CRS and HIPEC only. Three patients received only systemic chemotherapy. All patients with MCPM had only surgery. After a median follow‐up of seven years (2‐15), six patients (6/11; one death) with DMPM and two pati
Who reads Multicystic and Diffuse Malignant Peritoneal Mesothelioma in Children?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sophie Vermersch; Alexis Arnaud; Daniel Orbach; Nicolas Andre; Claire Berger; Vahan Kepenekian; Cécile Brigand; Brice Fresneau; Marie‐Laurence Poli‐Merol; Cyril Habougit; François Varlet; Aurélien Scalabre
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)