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Prognostic Significance of Pretreatment Controlling Nutritional Status Score in Urological Cancers: a Systematic Review and Meta‐analysis by Niu, Xinhao (author);Zhu, Zhe (author);Bao, Juan (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Prognostic Significance of Pretreatment Controlling Nutritional Status Score in Urological Cancers: a Systematic Review and Meta‐analysis about?
## Abstract ## Background Controlling Nutritional Status (CONUT) score is a novel nutrition-based biomarker that has been reported for predicting survival in various cancers. However, the relationship between CONUT score and prognosis of urological cancers remains unclear. Hence, we performed this meta-analysis to evaluate the prognostic significance of CONUT score for patients with urological cancers. ## Methods PubMed, Embase, the Cochrane Library and National Knowledge Infrastructure (CNKI) were systematically searched up to October 2020. The pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated to evaluate the association of CONUT score with overall survival (OS), cancer-specific survival (CSS) and recurrence/disease/progress-free survival (RFS/DFS/PFS) in urological cancers. ## Results A total of 12 articles with 13 studies were included in the analysis. Pooled results indicated that increased CONUT score predicted poor OS (HR: 1.78, 95% CI 1.51–2.09, p < 0.001), CSS (HR: 2.14, 95% CI 1.55–2.97, p < 0.001) and RFS/DFS/PFS (HR: 1.57, 95% CI 1.35–1.84, p < 0.001). Subgroup analysis by cancer type revealed that high CONUT score associated with worse OS in
Who reads Prognostic Significance of Pretreatment Controlling Nutritional Status Score in Urological Cancers: a Systematic Review and Meta‐analysis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Niu, Xinhao (author);Zhu, Zhe (author);Bao, Juan (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)
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