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Pyrazole Derivatives Combat Leishmania Infection by Rômulo Gabriel de Miranda de Paula PInto is a document available to read on EtoBox.
What is Pyrazole Derivatives Combat Leishmania Infection about?
The study investigates the efficacy of newly synthesized pyrazole carbohydrazide derivatives in treating murine cutaneous leishmaniasis caused by Leishmania amazonensis. Oral administration of these compounds significantly reduced lesion size and parasite burden without causing toxicity, as indicated by stable body weight and normal levels of liver and kidney function markers. The findings suggest that these derivatives may offer a promising alternative for leishmaniasis treatment, addressing the need for l
- Author
- Rômulo Gabriel de Miranda de Paula PInto
- Language
- EN