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Invasive Pulmonary Aspergillosis: Role of Early Diagnosis and Surgical Treatment in Patients with Acute Leukemia by Ridvan Ali; Fahir Ozkalemkas; Tulay Ozcelik; Vildan Ozkocaman; Atilla Ozkan; Sami Bayram; Beyza Ener; Ahmet Ursavas; Guze Ozal; Ahmet Tunali is a Medicine article available to read on EtoBox.

What is Invasive Pulmonary Aspergillosis: Role of Early Diagnosis and Surgical Treatment in Patients with Acute Leukemia about?

## Background __Aspergillus__ is a ubiquitous soil-dwelling fungus known to cause significant pulmonary infection in immunocompromised patients. The incidence of aspergillosis has increased during the past two decades and is a frequently lethal complication of acute leukemia patients that occurs following both chemotherapy and bone marrow transplantation. The diagnosis of invasive pulmonary aspergillosis (IPA) according to the criteria that are established by European Organization for the Research and Treatment of Cancer and Mycoses Study Group raise difficulties in severely ill patients. Despite established improvements in field of diagnosis (galactomannan antigen, quantitative PCR, real-time PCR for __Aspergillus__ spp., and findings of computed tomography) and treatment with new antifungals, it is still a major problem in patients with acute leukemia. However, prompt and effective treatment of IPA is crucial because most patients will need subsequent chemotherapy for underlying hematologic disease as soon as possible. ## Case presentation We report a 33-year-old male patient with acute promyelocytic leukemia diagnosed in 1993 that developed invasive pulmonary aspergillosis due t

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Author
Ridvan Ali; Fahir Ozkalemkas; Tulay Ozcelik; Vildan Ozkocaman; Atilla Ozkan; Sami Bayram; Beyza Ener; Ahmet Ursavas; Guze Ozal; Ahmet Tunali
Publisher
BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, [2002]-; Springer Science and Business Media LLC; Springer Nature (ISSN 1476-0711)
Published
2006
Language
EN
Field
Medicine (Health Sciences)

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