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Can I read High-throughput and multiplexed protein array technology: protein–DNA and protein–protein interactions on EtoBox?
High-throughput and multiplexed protein array technology: protein–DNA and protein–protein interactions by Vehary Sakanyan is a Chemistry article available to read on EtoBox.
What is High-throughput and multiplexed protein array technology: protein–DNA and protein–protein interactions about?
Miniaturized protein arrays address protein interactions with various types of molecules in a high-throughput and multiplexed fashion. This review focuses on achievements in the analysis of protein-DNA and protein-protein interactions. The technological feasibility of protein arrays depends on the different factors that enable the arrayed proteins to recognize molecular partners and on the specificity of the interactions involved. Proteome-scale studies of molecular interactions require high-throughput approaches for both the production and purification of functionally active proteins. Various solutions have been proposed to avoid non-specific protein interactions on array supports and to monitor low-abundance molecules. The data accumulated indicate that this emerging technology is perfectly suited to resolve networks of protein interactions involved in complex physiological and pathological phenomena in different organisms and to develop sensitive tools for biomedical applications.
Who reads High-throughput and multiplexed protein array technology: protein–DNA and protein–protein interactions?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Vehary Sakanyan
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-376X)
- Published
- 2005
- Language
- EN
- Field
- Chemistry (Physical Sciences)