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BetaSys : Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells by Bernhelm Booß-Bavnbek (editor), Beate Klösgen (editor), Jesper Larsen (editor), Flemming Pociot (editor), Erik Renström (editor) is a nonfiction available to read on EtoBox.

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Preface Acknowledgements Contents Contributors Part I Systems Biology Approach to β--Cells 1 Systems Biology of the β-Cell -- Revisited 1.1 Introduction 1.2 The β-cell and Diabetes 1.3 Genetics of Diabetes From GWA to NWA Studies The History of Diabetes 1.4 Why Systems Biology 1.5 Systems Biology How Ludwig von Bertalanffy (1901--1972) 1.6 Challenges of Methodological Advances 1.7 Summary 1.8 Understanding Pancreatic β-cell Death in Type 1 Diabetes -- A Systems Biology Approach 1.9 Conclusions References 2 Established Facts and Open Questions of Regulated Exocytosis in β-Cells -- A Background for a Focused Systems Analysis Approach 2.1 Introduction 2.2 The Basic Organization and Characteristics of the Exocytotic System in Pancreatic β-Cells 2.2.1 Synthesis of Insulin and Formation of Insulin Granules 2.2.2 Insulin Granule Transport to Release Sites Typical Length Scales (Rough Estimates of Diameters) in β-Cell Research 2.2.2.1 Directed and Random Granule Movement 2.2.2.2 Cytoskeleton and Motor Proteins in the β-Cell 2.2.3 Functional Insulin Granule Pools and the Relation to Phasic Insulin Secretion Observation Means and Scales -- From Light Microscopy to Electron Microscopy 2.2.

Who reads BetaSys : Systems Biology of Regulated Exocytosis in Pancreatic ß-Cells?

Author

Bernhelm Booß-Bavnbek (editor), Beate Klösgen (editor), Jesper Larsen (editor), Flemming Pociot (editor), Erik Renström (editor)

Publisher

Springer Science+Business Media, LLC

Published

2011

Language

EN

ISBN

9781461428152

Category

nonfiction

Subjects

Science, Medical, Biology