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Congenital adrenal hyperplasia in children – a survey on the current practice in the UK by Usha Niranjan; Anuja Natarajan is a Medicine article available to read on EtoBox.
What is Congenital adrenal hyperplasia in children – a survey on the current practice in the UK about?
Background: Congenital adrenal hyperplasia (CAH) in children varies in presentation and progression with several challenges in optimal management. Effective treatment is to achieve normal growth and development while avoiding adrenal crisis and hyperandrogenisation. Aim: Our aim was to ascertain the current practice in the UK on CAH management in children in comparison with the recommendations made by the Endocrine Society. Methods: An online survey was emailed to the British Society of Paediatric Endocrinology (BSPED) members requesting a response from each centre regarding CAH management. ## Results: The survey was completed by 35 out of 92 centres (38% response rate). Tertiary centres constituted 22/35, while 8/35 were district general hospitals providing tertiary services. Treatment varied among centres with 25/35 using 10-15 mg/m 2 /day of hydrocortisone and 21/35 of centres using 50-150 μg/day of fludrocortisone. The frequency of clinical reviews was contentious and varied depending on the child's age and clinical status. Reviews were done 3-4 monthly in 68% and 6 monthly in 31% of centres. The frequency of investigations including 17-hydroxyprogesterone (66% 3-6 monthly; 34%
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- Author
- Usha Niranjan; Anuja Natarajan
- Publisher
- Walter de Gruyter GmbH
- Published
- 2015
- Language
- EN
- Field
- Medicine (Health Sciences)