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This study investigates the predictive value of cerebrospinal fluid (CSF) markers, specifically VILIP-1, tau, and p-tau181, for brain atrophy rates in early Alzheimer Disease (AD) and cognitively normal controls over a follow-up of 2 to 3 years. Results indicate that baseline levels of CSF VILIP-1, along with tau and p-tau181, significantly predict rates of whole-brain and regional atrophy, with VILIP-1 showing comparable predictive power to tau and p-tau181. The findings suggest that CSF VILIP-1 may serve

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naija

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EN