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Can I read Biomimetic Calcium Phosphate Coated Macro-Microporous Poly(ε-caprolactone)/Silk Fibroin (PCL/SF) Scaffold for Bone Tissue Engineering on EtoBox?
Biomimetic Calcium Phosphate Coated Macro-Microporous Poly(ε-caprolactone)/Silk Fibroin (PCL/SF) Scaffold for Bone Tissue Engineering by Nomin-Erdene Tumursukh; Joo Hee Choi; Jin Sol Seo; Youngeun Song; Gayeong Jeon; Na Eun Kim; Jeong Eun Song; Gilson Khang is a Materials Science article available to read on EtoBox.
What is Biomimetic Calcium Phosphate Coated Macro-Microporous Poly(ε-caprolactone)/Silk Fibroin (PCL/SF) Scaffold for Bone Tissue Engineering about?
Because of an aging population and social development, tissue engineering techniques have been widely studied and used for patient treatment. To improve bone regeneration and overcome disadvantages, suitable biomaterials have to be chosen. Polycaprolactone (PCL) is extensively used in bone tissue engineering, known for its excellent mechanical properties, high crystallinity, toughness, and biocompatibility. In addition, porous PCL can induce bone ingrowth into its macropores and can be used for the repair and regeneration of the bone. However, PCL has limited cell affinity primarily owing to the lack of cell recognition sites due to its hydrophobic surface. To compensate drawbacks of PCL scaffolds, silk fibroin (SF), nonsolvent and thermal-induced phase separation (N-TIPS), and salt-leaching were utilized in this study. Additionally, to overcome the disadvantage that the polymeric scaffold may be insignificant for osteoinduction, PCL/SF scaffolds were coated with calcium phosphate (CaP) (c-PCL/SF). Physicochemical properties, biological activity, and mechanical characters were analyzed to confirm applicability in bone tissue engineering. Also, in vitro study was performed with viab
Who reads Biomimetic Calcium Phosphate Coated Macro-Microporous Poly(ε-caprolactone)/Silk Fibroin (PCL/SF) Scaffold for Bone Tissue Engineering?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Nomin-Erdene Tumursukh; Joo Hee Choi; Jin Sol Seo; Youngeun Song; Gayeong Jeon; Na Eun Kim; Jeong Eun Song; Gilson Khang
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Materials Science (Physical Sciences)