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Structure and Function of Intrinsically Disordered Proteins by Peter Tompa, Alan Fersht is a nonfiction available to read on EtoBox.

What is Structure and Function of Intrinsically Disordered Proteins about?

<p>The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug development. <b>Structure and Function of Intrinsically Disordered Proteins</b> thoroughly covers the history up to the latest developments in this field.</p> <p>After examining the principles of protein structure, the classical paradigm, and the history of structural disorder, the book focuses on physical techniques for the identification and characterization of IDPs. It discusses proteomic and bioinformatic approaches and shows how IDPs behave under crowding conditions in living cells. The next several chapters describe the structure, correlating biological processes, and molecular mechanisms of IDPs. The author also explores the evolutionary advancement of structural disorder in proteomes and possible ways of extending the structure-function paradigm to encompass both ordered and disordered states of proteins. He concludes with discuss

Who reads Structure and Function of Intrinsically Disordered Proteins?

Author

Peter Tompa, Alan Fersht

Publisher

CRC Press Taylor & Francis

Published

2009

Language

EN

ISBN

9781420078930

Category

nonfiction

Subjects

Science, Technology, Chemistry