About this document

G4 Docking Spec Studies by shreyashaz05 is a document available to read on EtoBox.

This study investigates the binding and interaction of curcumin-cysteine conjugate (CC) and rosmarinic acid (RA) with human telomeric G-quadruplex DNA using spectroscopic and molecular docking methods. Results indicate that CC exhibits superior binding capabilities compared to RA, with CC binding through both minor and major grooves of the DNA, while RA binds only through the minor groove. The findings suggest potential applications for these ligands in anticancer drug development targeting G-quadruplex str

Author

shreyashaz05

Language

EN