Can I read Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital on EtoBox?

Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital by Delorme, Clara; Viel-Thériault, Isabelle; Moradipour, Tassnim; Le Saux, Nicole is a Medicine article available to read on EtoBox.

What is Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital about?

Background: Ceftriaxone is frequently used as empiric therapy because of its broad spectrum and dosing characteristics. The purpose of this study was to evaluate the appropriateness of ceftriaxone therapy among hospitalized children using drug use evaluation (DUE) methodology. Methods: Hospitalized patients who received one or fewer dose of intravenous ceftriaxone at Children’s Hospital of Eastern Ontario between January 1, 2018, and June 30, 2018, were identified. Duration was defined as empiric if 72 or less and definitive if more than 72 hours. Two infectious disease physicians reviewed the charts and rated appropriateness using a previously developed scale. Results: A total of 276 ceftriaxone courses in 248 patients (mean age 6.0 y) were reviewed. Of these, 153 (55.4%) were assessed as definitively or possibly indicated. The most common reason for inappropriate empiric use was an overly broad spectrum. Of the 120 courses given empirically for which there was no indication, the three most common reasons were lower respiratory infections (51; 42.5%), head and neck infections (18; 15.0%), and intra-abdominal infections (15; 12.5%). Of the 39 (14.1%) courses of ceftriaxone that wer

Who reads Drug use evaluation (DUE) of ceftriaxone: A quality metric in a pediatric hospital?

Author

Delorme, Clara; Viel-Thériault, Isabelle; Moradipour, Tassnim; Le Saux, Nicole

Publisher

University of Toronto Press Inc; Oakville Ontario Canada: Pulsus Group Inc., [2016]-; University of Toronto Press Inc. (UTPress) (ISSN 2371-0888)

Published

2020

Language

EN

Field

Medicine (Health Sciences)