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Patch Testing in Children and Adolescents with Contact Dermatitis by Moraes, Priscila; Bertocco Andrade, Maria Elisa; Rufino Pereira, Veridiana Aun; Bezerra Filho, Carlos Alves; Alevato, Daniele Maciel; Rodrigues, Adriana Teixeira; Fernandes, Fatima Rodrigues is a Medicine article available to read on EtoBox.

What is Patch Testing in Children and Adolescents with Contact Dermatitis about?

RATIONALE: Atopic dermatitis (AD) is a chronic disease characterized by itchy inflamed skin. We investigated the profile of allergen sensitization in adult patients with AD using multiplexed allergen microarray. METHODS: 39 patients with moderate and severe AD, attending the Allergy or Dermatology Clinics at our Institution, were enrolled. Total and specific IgE were quantitated by ImmunoCAP and ImmunoCAP-ISACÒ, respectively. RESULTS: Patients were aged 14-66 years-old (mean 6 SD 34.3 6 2.1 years), 64% female. Mean SCORAD was 36.6(2-90). Geometric mean (GM) of total IgE was 1,963 UI/mL (24-63,000UI/mL). Allergens from dust mites were dominant, with sensitization to Derp1, and to Derf1, Derp2, and Derf2 in 82% and 85% patients, with GM 27.6;50.0;39.2;45.4 ISU-E, respectively, followed by cat (38%), dog (36%) and grass pollen (36%) allergens. IgE to allergens from cockroach, fungi, most tree and weed pollens, latex and insect venoms was found in <20% of patients at low levels. Sensitization to walnut (33%), shrimp (31%), olive (28%) and peach (26%) allergens was most prevalent among foods, whereas IgE reactivity to milk and egg was present in 10% or less of the patients, with low lev

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Author
Moraes, Priscila; Bertocco Andrade, Maria Elisa; Rufino Pereira, Veridiana Aun; Bezerra Filho, Carlos Alves; Alevato, Daniele Maciel; Rodrigues, Adriana Teixeira; Fernandes, Fatima Rodrigues
Publisher
Elsevier Science; Elsevier ; Mosby Inc.; Elsevier BV; SAGE Publications (ISSN 1097-6825)
Published
2018
Language
EN
Field
Medicine (Health Sciences)