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What is Engineered TdT for RNA Primer Elongation about?

This study presents the rational design of Terminal Deoxynucleotidyl Transferase (TdT) to enhance its ability to elongate RNA primers, achieving an increase in RNA elongation activity from 20% to over 90%. By engineering the primer recognition site of TdT, the researchers developed RNA-editing enzymes that can be adapted for various applications in nucleic acid synthesis and synthetic biology. The findings indicate that the engineered TdTs can effectively recognize and extend RNA primers, providing a signif

Author

parkhr0124

Language

EN