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A new soft-particle DEM model of micro-particle impact integrated adhesive, elastoplastic and microslip behaviors by Dong, Yunshan; Si, Fengqi; Jin, Wei; Cao, Yue; Ren, Shaojun is a Engineering article available to read on EtoBox.

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Angioscopy enables macroscopic pathological diagnosis of cardiovascular diseases from the inside. This imaging modality has been intensively directed to characterizing vulnerable coronary plaques. Scoring of plaque color was developed, and based on prospective studies; dark yellow or glistening yellow plaques were proposed as vulnerable ones. Colorimetry apparatus was developed to assess the yellow color of the plaques quantitatively. The effects of lipid-lowering therapies on coronary plaques were confirmed by angioscopy. However, since observation is limited to surface color and morphology, pitfalls of this imaging technology became evident. Dye-staining angioscopy and near-infrared fluorescence angioscopy were developed for molecular imaging, and the latter method was successfully applied to patients. Color fluorescence angioscopy was also established for molecular and chemical basis characterization of vulnerable coronary plaques in both in vitro and in vivo. Drug-eluting stents (DES) reduce coronary restenosis significantly, however, late stent thrombosis (LST) occurs, which requires long-term antiplatelet therapy. Angioscopic grading of neointimal coverage of coronary stent s

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Author

Dong, Yunshan; Si, Fengqi; Jin, Wei; Cao, Yue; Ren, Shaojun

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0921-8831)

Published

2020

Language

EN

Field

Engineering (Physical Sciences)