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This document contains a PICO worksheet for developing a clinical question and search strategy about the effects of esomeprazole (PPI) treatment on bone fracture risk in elderly patients. The patient population is a 75-year old woman with GERD and a bone fracture who receives daily esomeprazole treatment. The intervention is esomeprazole and the comparison is no esomeprazole treatment. The outcome of interest is the risk of bone fracture with PPI use. Search terms identified include esomeprazole, PPI, GERD,

Author

Zanquen Heinry

Language

EN