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Outcomes of Adverse Drug Events Reported with Potentially Inappropriate Medications in Older Adults, 2004–2017 by Sharon K. Park; Bao Tran Luu is a Medicine article available to read on EtoBox.

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Background: Prescribing of potentially inappropriate medications (PIMs) in adults who are ≥65 years old have been associated with adverse drug events (ADEs). Aim: To describe ADEs with PIMs in the older adults based on demographics, ADE severity level, and medication class. Method: All ADEs reported to the U.S. Food and Drug Administration Adverse Event Reporting System between 1 January 2004 and 31 December 2017 were reviewed. Data were collected for any ADEs associated with PIMs in adults with ages ≥65 years per the Beers Criteria, including demographics, ADE severity, and ADE date. ADEs were further analysed for any death, hospitalisation, disability, and other serious outcomes associated with PIMs. Data were analysed descriptively. Results: The number of reported ADEs increased steadily over the 13-year period. Of the total 68 762 ADEs reported, 80.4% were serious ADEs and more women experienced ADEs (52.0%) than men (46.4%). Age group between 65-74 had a higher number of ADE reports than other groups. Of the 55 302 serious ADEs, 2723 were deaths. The anticoagulants class had the highest percentage of ADEs with death outcomes (57.3%), followed by cardiovascular drugs. An estima

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Author

Sharon K. Park; Bao Tran Luu

Publisher

Wiley

Published

2021

Language

EN

Field

Medicine (Health Sciences)