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This review discusses advancements in the trifluoromethylation of C(sp3)-H bonds, highlighting its significance in organic synthesis, pharmaceuticals, and agrochemicals. It covers various methodologies for activating relatively inert C(sp3)-H bonds, including metal catalysis, light-induced approaches, and organocatalysis, while also addressing the mechanisms and future prospects in this field. The review aims to serve as a comprehensive resource for chemists working with fluorinated compounds and to inspire

Author

sirnaveen79

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EN