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This document reviews the role of mineralocorticoid receptor (MR) activation and mineralocorticoid receptor antagonists (MRAs) in cardiac and renal diseases, highlighting their pathophysiological mechanisms and therapeutic implications. It discusses how aldosterone influences both organs, leading to detrimental effects such as myocardial hypertrophy and renal injury, and emphasizes the clinical benefits of MRAs in reducing mortality and morbidity in heart failure patients. The findings underscore the import

Author

agdias

Language

EN