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Can I read Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study on EtoBox?

Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study by Zaia, Annamaria (author);Rossi, Roberto (author);Galeazzi, Roberta (author);Sallei, Manuela (author);Maponi, Pierluigi (author);Scendoni, Pietro (author) is a Medicine article available to read on EtoBox.

What is Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study about?

## Abstract ## Background Osteoporotic fractures are a major cause of morbidity in the elderly. Menopausal women represent the population with the highest risk of early osteoporosis onset, often accompanied by vertebral fractures (VF). Bone mineral density (BMD) is commonly assessed by dual-energy X-ray absorptiometry (DXA) for osteoporosis diagnosis; however, BMD alone does not represent a significant predictor of fracture risk. Bone microarchitecture, instead, arises as a determinant of bone fragility independent of BMD. High-resolution magnetic resonance imaging (MRI) is an effective noninvasive/nonionizing tool for in vivo characterisation of trabecular bone microarchitecture (TBA). We have previously set up an MRI method able to characterise TBA changes in aging and osteoporosis by one parameter, trabecular bone lacunarity parameter β (TBLβ). Fractal lacunarity was used for TBA texture analysis as it describes discontinuity of bone network and size of bone marrow spaces, changes of which increase the risk of bone fracture. This study aims to assess the potential of TBLβ method as a tool for osteoporotic fracture risk. ## Methods An observational, cross-sectional, and prospecti

Who reads Fractal lacunarity of trabecular bone in vertebral MRI to predict osteoporotic fracture risk in over-fifties women. The LOTO study?

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Author
Zaia, Annamaria (author);Rossi, Roberto (author);Galeazzi, Roberta (author);Sallei, Manuela (author);Maponi, Pierluigi (author);Scendoni, Pietro (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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