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Application of Digital Subtraction Angiography in Canine Hindlimb Arteriography by Xue Wang; Lubin Li; Chengwei Wang; Shiyong Zhang; Jie Wang; Tiannan Chen is a Medicine article available to read on EtoBox.

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## Objectives Research in the field of lower extremity vascular disease has increased in popularity over the years. To adequately characterize and validate the effectiveness of vascular interventions, in vivo experimentation in large animals is required. Thus, it is necessary to find a method to detect the shape and density of blood vessels in the lower extremities that can evaluate and verify the treatment measures’ effectiveness and have high accuracy and repeatability. This study characterized factors that determined both the accuracy and overall value of digital subtraction angiography in lower limb arteriography using a canine animal model. ## Methods Six beagle dogs were anesthetized and immobilized on the motorized table. The femoral artery was accessed using an indwelling needle. A bolus of contrast agent was injected into the access site, and digital subtraction angiography with bolus chase technology was used to collect contrast images for analysis. At the end of the procedure, the anesthetized dogs were euthanized using an overdose of potassium chloride. After confirming the euthanasia of the dogs, the cadavers were taken to the experimental animal center of Xinjiang Med

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Author

Xue Wang; Lubin Li; Chengwei Wang; Shiyong Zhang; Jie Wang; Tiannan Chen

Publisher

SAGE Publications

Published

2021

Language

EN

Field

Medicine (Health Sciences)