Can I read History of Pineal Gland as Neuroendocrine Organ and the Discovery of Melatonin on EtoBox?

History of Pineal Gland as Neuroendocrine Organ and the Discovery of Melatonin by López-Muñoz, Francisco; Srinivasan, Venkataramanujam; de Berardis, Domenico; Álamo, Cecilio; Kato, Takahiro A. is a scholarly article available to read on EtoBox.

What is History of Pineal Gland as Neuroendocrine Organ and the Discovery of Melatonin about?

This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders. Mood disorders such as major depressive disorder (MDD), bipolar disorder (BPD) and seasonal affective disorder (SAD) are the most disabling disorders that are among the most expensive of all medical illnesses. The pathophysiology of mood disorders is very complex and involves many mechanisms like circadian rhythm disruption, sleep abnormalities, melatonin rhythm abnormalities and alterations in melatonin receptor mechanisms, abnormalities in monoaminergic neurotransmitter mechanisms, glutamatergic release mechanisms, hippocampal neurogenesis, and abnormal immune and cytokine release mechanisms. Many antidepressants that are in clinical use today including the recently introduced novel agents like agomelatine or other antidepressants cause clinical remission by resynchronizing disrupted circadian rhythms and melatonin receptor functions, enhancing monoaminergic neurotransmission, promoting hippocampal neurogenesis

Author

López-Muñoz, Francisco; Srinivasan, Venkataramanujam; de Berardis, Domenico; Álamo, Cecilio; Kato, Takahiro A.

Publisher

Springer India : Imprint: Springer

Published

2016

Language

EN

ISBN

9788132228035