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Can I read Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia on EtoBox?
Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia by Fortunato Morabito; Massimo Mangiola; Bianca Oliva; Caterina Stelitano; Vincenzo Callea; Silvia Deaglio; Pasquale Iacopino; Maura Brugiatelli; Fabio Malavasi is a Medicine article available to read on EtoBox.
What is Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia about?
CD38 expression was investigated in 161 untreated patients with B-cell chronic lymphocytic leukemia (B-CLL). A score system, devised ad hoc by integrating the percentage and the mean fluorescence intensity (MFI) values of CD38 + cells, indicated that B-CLL patients with a CD38 score 53 are characterized by a significantly longer survival compared to those with a CD38 score \ 3 (P = 0.0026). Thirty-seven percent of patients with a CD38 score 5 3 and 58% of those with a score \3 were dead at 10 years. Multivariate analysis indicates that only the CD38 score successfully predicts survival (P= 0.0028), with an estimated 3.8-fold greater risk of death for those cases with CD38 score \ 3.
Who reads Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Fortunato Morabito; Massimo Mangiola; Bianca Oliva; Caterina Stelitano; Vincenzo Callea; Silvia Deaglio; Pasquale Iacopino; Maura Brugiatelli; Fabio Malavasi
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0145-2126)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)