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Effect of Home Bleaching and Smoking on Marginal Gingival Epithelium Proliferation: a Histologic Study in Women by Luiz Cesar Da Costa Filho; Carolina Covolo Da Costa; Marina Lara Sória; Rumio Taga is a Medicine article available to read on EtoBox.

What is Effect of Home Bleaching and Smoking on Marginal Gingival Epithelium Proliferation: a Histologic Study in Women about?

## Abstract **Background:** Animal studies have suggested that home bleaching agents can cause morphological alterations and changes in the proliferative rate of oral epithelium. **Methods:** A bleaching agent containing 10% carbamide peroxide with carbopol was used in 11 women (five smokers and six non‐smokers) during a 5‐week period. Two biopsies were performed, one of them 15 days before the beginning of the home bleaching treatment and the other immediately after the 5‐week bleaching treatment. Two analyses were performed in the histological sections obtained from the biopsies: epithelium morphometry and assessment of the epithelium's proliferative activity by proliferating cell nuclear antigen (PCNA) immunohistochemistry. **Results:** The home bleaching agent increases epithelium thickness and the PCNA index in both smoker and non‐smoker patients. **Conclusion:** Carbamide peroxide (10%) caused an augmentation in the proliferative activity within the basal and parabasal layers of the gingival epithelium, resulting in a change in this tissue's morphometry.

Who reads Effect of Home Bleaching and Smoking on Marginal Gingival Epithelium Proliferation: a Histologic Study in Women?

Author

Luiz Cesar Da Costa Filho; Carolina Covolo Da Costa; Marina Lara Sória; Rumio Taga

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0904-2512)

Published

2002

Language

EN

Field

Medicine (Health Sciences)