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Effects of Korean Red Ginseng on Cognitive and Motor Function: A Double-blind, Randomized, Placebo-controlled Trial by Yeo, Hye-Bin; Yoon, Ho-Kyoung; Lee, Heon-Jeong; Kang, Seung-Gul; Jung, Ki-Young; Kim, Leen is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Ginseng has a long history of use for health enhancement, and there is some evidence from animal studies that it has a beneficial effect on cognitive performance. The purpose of this study was to investigate the effect of Korean red ginseng on cognitive performance in humans. A total of 15 healthy young males with no psychiatric or cognitive problems were selected based on an interview with a board-certified psychiatrist. The subjects were randomly assigned to receive a daily dose of 4,500 mg red ginseng or placebo for a 2-week trial. There were 8 subjects in the red ginseng group and 7 subjects in the placebo group. All of the subjects were analyzed with the Vienna test system and a P300 event-related potential (ERP) test. There were no significant differences in the Vienna test system scores between the red ginseng group and the placebo group. In the event-related potential test, the C3 latency of the red ginseng group tended to decrease during the study period (__p__=0.005). After 2 wk, significant decreases were observed in the P300 latencies at Cz (__p__=0.008), C3 (__p__=0.005), C4 (__p__=0.002), and C mean (__p__=0.003) in the red ginseng group. Our results suggest that the

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Author

Yeo, Hye-Bin; Yoon, Ho-Kyoung; Lee, Heon-Jeong; Kang, Seung-Gul; Jung, Ki-Young; Kim, Leen

Publisher

Elsevier ; Elsevier BV; Seoul: Korean Society of Ginseng; Seoul: Elsevier Korea LLC (ISSN 1226-8453)

Published

2012

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)